Detection and Control of Biofilm Produced by Pathogenic Bacteria

Vidya Sunil Tale


A bacterial biofilm is a structured community of bacterial cells enclosed in a self-produced polymeric matrix that is adherent to an inert or living surface. The stages involving attachment, colonization and growth that leads to establishment of a mature biofilm colony formation.  There are different assay for the detection of bacterial biofilms like staining assay include FDA assay, LIVE/DEAD BacLight assay, XIT assay etc. and genetic assay include PCR technique. Control of bacterial biofilms include using phages, nanoparticles and control using anti-adhesion agents like mannosides, pillicides and curlicides and using anti-matrix agents like enzymes and chelating agents.

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