Effects of L-Carnitine Tartrate Acute Consumption on free fatty acid and Lactate blood and distance traveled Following Aerobic Exhaustive Exercise on Treadmill in Elite Athlete

Rahim Mir Nasuri


Background and purpose: Despite many studies on the main mechanisms of the function of L-carnitine, some processes of its supplementation effects on lipid metabolism in healthy humans are still unknown. Therefore, this study was conducted to determine the effects of short-term oral supplementation of L-carnitine on lipid and blood lactate metabolisms in endurance exercise performance.

Materials and methods: Twenty healthy exercised men participated in this single blind clinical trial. Subjects were selectively divided into the two supplemented (n = 10) and placebo (n = 10) groups. The supplement group received 3 g of L-carnitine tartrate dissolved in 200 ml of water plus 6 drops of lemon juice while the placebo group received only 200 ml of water plus 6 drops of lemon juice, 90 minutes before performing the protocol outlined by Conconi. Blood samples were drawn from the arm vein at 90 minutes before, immediately after and 30 minutes of rest after the exercise and their free fatty acid and blood lactate and concentrations were measured using standard kits.

Results: In the experimental group, significant difference was observed in free fatty acid, blood lactate  and distance traveled concentrations. Moreover, in the control group, the dependent variables showed no significant changes due to placebo (P<0/05).

Conclusion: The results of the present study showed that supplementation of L-carnitine improved effective endurance performance by reducing blood lactate. However, no significant effect was observed on triglyceride.


L-carnitine tartrate, free fatty acid, Lactate blood, exhaustive aerobic activity

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