Renuka Jayachandran


Aim: Proliferative diabetic retinopathy (PDR) is a more serious clinical presentation of diabetic retinopathy. Panretinal photocoagulation (PRP) is an effective laser treatment for PDR. The heat from the laser shrinks the blood vessels to prevent them from re-growing. However, in most cases, severe visual loss still develops despite therapy. The aim of this study was to examine the effect on visual acuity after PRP in PDR by conducting a systematic review.

Methods: The search was systematically done on seven databases; MEDLINE, SCIENCE DIRECT, CINAHL COMPLETE, COCHRANE, SCOPUS, WEB OF SCIENCE and EMBASE. The search focused on any studies related to the effect of PRP on visual acuity in PDR. The search strategies were done by using keywords related to “Proliferative Diabetic Retinopathy”, “Panretinal Photocoagulation” and “Visual Acuity”.

Results: A total of 1775 abstracts were initially identified. 575 abstracts were removed after duplication. The remaining of 1200 abstracts were reviewed by looking at the titles, abstracts and full papers using pre-determined inclusion and exclusion criteria, after which only two were included in the review. These two studies showed that there is loss on visual acuity immediately after PRP treatment on PDR, but time to the recovery of vision varies from nine days to three months.

Conclusion: There were only two studies on the effect of PRP on visual acuity in PDR. Therefore, more research which specifically focused on the effect of PRP should be carried out to investigate more on the effectiveness of the treatment. 


Diabetes; Diabetic Mellitus; Eye; Laser; Laser Photocoagulation; Proliferative Diabetic Retinopathy; Visual Acuity

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