Prevalence of Hepatitis B and Hepatitis C in Transfusion Dependent Thalassemia Patients

Arfa Goheer, Irsa Abbasi, Asma Cheema

Abstract


Objective:To determine the prevalence of transfusion transmitted diseases like viral hepatitis B and C in thalassaemic patients.

Study Design: Descriptive / cross section study

Place and Duration of Study: The study was carried out from Jan 2018 to Mar 2018 at the Paediatrics Department, Sheikh Khalifa Bin Zayed Teaching Hospital, Rawalakot, AJK Teaching Hospital of Poonch Medical College, Rawalakot.

Materials and Methods:There were 55 patients of thalassaemic who were screened for transfusion transmitted hepatitis B & C virus with the use of electro chemiluminescenceauto analyserelecsysCobas E 411 and where possible PCR techniques. The result i.e., infection of hepatitis B & C was stratified by age, equality and duration of transfusion.

Results: There was 30/91% prevalence of transfusion transmitted hepatitis C in the current research and it had a statistically significant association with the age and duration of blood transfusion in thalassaemic patients.None of the patient had positive Hepatitis B.

Conclusion: High prevalence of transfusion transmitted hepatitis C in thalassaemic patients notwithstanding adoption of donor blood screening protocols requires to be addressed on urgent basis for the determination of elements causing this transfusion therapy complication.

Key Words: Chelation,Cirrhosis liver, Hepatitis C,Transfusion,Thalassemia,Viral Hepatitis


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