Vaginal V/S Intramuscular Use of Progesterone and its Efficacy in preventing the preterm labor: A comparative Study.

Muhammad Zahid, Muhammad Waqas Saleem, Tassarun imtiaz

Abstract


Abstract:

Objective: The main aim of this study was to find the efficacy of use of progesterone either vaginally or intramuscularly in avoiding the preterm labor.

Place of Study: This study was carried out in Gynecology and Obstetrics department of Sir Ganga Ram Hospital Lahore.

Duration of study: This study was carried out in a duration of 9 months from February 2018 to October 2018.

Materials and Methods: A total of 200 patients were selected and divided into two groups having 100 patients in each group. The patients were between the ages of 25 to 35 years with parity five. In all the patients history of preterm delivery was present and they were at 20 to 24th week of gestation. Vaginal administration of 200mg progesterone was done (pessary) once a day in group A while weekly administration of 250mg was given intramuscularly. It was continued till 37th completed weeks. The follow up of the patients was strictly observed and maintained via telephonic contact.

Results: Progesterone administered vaginally had higher efficacy of 71% in preventing the preterm labor as compared to intramuscular route in which efficacy of 52% was noted.

Conclusion: Progesterone given to the patient via vaginal route has greater efficacy in preventing the preterm labor as compared to the ones in which Intramuscular route was used for progesterone administration.

Keywords: progesterone, intramuscular, vaginal, efficacy.


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