Rheumatoid arthritis related presentation of different types of anemia and their evaluation.

Tassarun imtiaz, Muhammad Waqas Saleem, Muhammad Zahid, Saddam Hussain Abbasi

Abstract


Abstract:

Objective: The main aim of this study was to find the incidence of Rheumatoid arthritis related presentation of different types of anemia and their evaluation.

Type of study: It is a cross sectional study.

Place and duration of study: This study was carried out in a duration of 9 months from February 2018 to October 2018 in rheumatology department of Fatima Memorial Hospital Lahore.

Materials and Methods: A total of 100 patients were selected among which 50 were diagnosed with Rheumatoid arthritis and 50 had no problem and they were taken as control cases. 50 cases which were diagnosed with RA included both males and females. Informed consent was taken from all the patients who were willing to take part in this study.   

The patients who had chronic co-morbidities like liver diseases, renal failure, severe lung diseases or any malignancy were excluded from the study.

Results: Among all the patients who had RA anemia was seen in 60% of the patients and 40% of the patients demonstrated no signs of anemia as shown by the Hb, PCB, RBC values which were significantly reduced in rheumatoid arthritis associated anemia as compared to the ones who had no signs of anemia. In RA associated anemia MCH levels were significantly reduced as compared to non-anemic rheumatoid arthritis patients while normal values were seen for MCHC and MCV. Reduced levels of serum ferritin were seen in 7 patients who had anemia associated with RA while 23 patients had normal levels of ferritin. 23% of the patients of RA had iron deficiency anemia while anemia of chronic disease was found in 77% of the patients.

Conclusion: Two types of anemia are associated with RA.

1- Iron deficiency anemia

2- Anemia of chronic disease

According to the stats anemia of chronic disease is more common in patients with rheumatoid arthritis patients.

Keywords: Iron deficiency anemia, rheumatoid arthritis, anemia of chronic disease.


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