Clinical Presentation Of Epithelial Ovarian Carcinoma

Amina Safdar, Aamna Tariq

Abstract


Objective:  To determine various modes of presentation of patients having epithelial ovarian carcinoma

Study design and duration: This is a cross sectional study of observational type.Study consists on the duration of six months.

Setting: This study was conducted in general surgical and chemotherapy ward of  Nishtar Hospital Multan.

Patients and Methods:  All cases diagnosed with epithelial ovarian cancer presenting to the study institution during study period were included in this study. A performa was designed containing necessary questions like signs and symptoms at the time of first presentation, menopausal status, age of patient, family history of similar problem etc. Questions were asked in simplified way and their answers were noted down. Grade of tumors was also documented. All data collected was analyzed using SPSS and Microsoft office version 2016. Results were calculated in the form of frequencies and percentages and averages. Tables and Graphs used to present data. Consent was taken from ethical committee of the study hospital and consent was also taken from all cases in study group.

Results: Total 60 cases were included in the study. 5% cases were below 20 years age, 25% were between 20-30 years, 16.7% between 30-40 years, 20% between 40-50 years, 23.3% between 50-60 years and 10% cases were above 60 years of age. Mean age was 44.6 years. There was positive family history in 25% cases. 78.3% cases were in premenopausal and 21.7% in post menopausal status. There were 8.3% cases in first stage, 16.7% in second stage,55% in 3rd stage and 20% were in 4th stage of cancer at the time of presentation. Pathological grade reported was well differentiated in 30%, moderately differentiated in 41.7%, poorly differentiated in 18.3% and unknown grade in 10%.

Conclusion: Epithelial ovarian cancer is mostly found in young women and usually is reported in late stages. High frequency of positive family history is found in these cases.


Keywords


epithelial ovarian cancer, clinical presentation, family history

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