Diagnostic Role of Typhidot in the Diagnosis of Typhoid Fever
Objective: The main aim of this study was to find the efficacy and diagnostic value of typhidot for diagnosing the typhoid fever.
Place and Duration of study: This study was carried out in a duration of one year from December 2017 to November 2018 in Jinnah Hospital Lahore.
Materials and Methods: The patients presenting in the GI clinic of Jinnah Hospital Lahore were considered for the study. Males and females of all the ages were taken into consideration regardless of their gender. Patients were selected on the basis of history and clinical examination and later on tests were performed to confirm the diagnosis. The patients who had high grade step ladder fever as well as diarrhea were considered for the study. On 4th day typhidot was performed on all the patients and later on blood culture was done. True positive were the patients in which both typhidot and blood culture was positive and false positive were the patients in which typhidot was positive but blood culture was negative. The best diagnostic test for typhoid is blood culture but it is expensive and time consuming due to which it cannot be relied upon. Hence a cheap test is needed and most of the physicians opt for typhidot which is neither sensitive nor specific for typhoid. This study was done to find out the reliability of typhidot for diagnosing the typhoid fever. Informed consent was taken from all the patients or their relatives. Ethical committee approval was taken.
Results: Our study included 70 patients and 32 patients among these were found positive according to typhidot and among these positive blood culture was seen in 16 (50%) of the patients while negative blood culture was seen in 16 (50%) of the patients. 38 remaining patients were negative for the typhidot and even among those positive blood culture was seen in 23 (60.52%) of the patients while 15 (39.48%) of the patients had negative blood culture.
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