Comparing the Levels of Low Density Lipoproteins with Incidence of Hemorrhagic and Ischemic Stroke

Mohsin Irshad Abbasi, Ahsan Ali Gaad, Zeeshan Murtaza

Abstract


Objective: The main aim of this study was to find a correlation between levels of low density lipoproteins with hemorrhagic and ischemic stroke.

Place and Duration of Study: This study was carried out in a duration of 5 months from June 2019 to October 2019 in medical units of Jinnah Hospital Lahore.

Materials and Methods: A total of 310 patients were selected for this study. Both genders were included in this study between the ages of 20 to 70 years. Diagnosis of hemorrhagic or ischemic stroke was made on the basis of CT scan. Levels of low density lipoproteins were calculated via venous samples collected carefully after overnight NPO for 8 hours and then sent to a reliable laboratory for analysis. Relatable information like confidence variables including hypertension, fasting BSR>110, diastolic blood pressure>90mmHg, systolic blood pressure>140, and levels of low density lipoproteins are specifically indicated. Results of all the patients were used to measure the means LDL levels and then compared with the patients having hemorrhagic or ischemic stroke. Informed consent was taken from the relatives of the patients. Hospital ethical committee approval was taken. Data was collected on a carefully designed proforma and then analyzed using SPSS version 20.

Results: In our study, patients between the ages of 20-50 years were 132 (41.25%) and patients between the ages of 51-70 years were 188 (58.75%). Mean and standard deviation was 47.65 + 5.32 years. In our study, male patients were 199 (69.19%) and female patients were 121 (37.81%). Hemorrhagic stroke was found in 31 (9.69%) while ischemic stroke was found in 290 (90.31%). Comparison of serum low density lipoproteins levels with ischemic and hemorrhagic stroke showed 98.65 +3.76 in hemorrhagic stroke while 127.21 + 34.31 was seen in cases of ischemic stroke.

Conclusion: Results of our study show that ischemic stroke is more likely to occur with increasing levels of low density lipoproteins as compared to hemorrhagic stroke. To reduce the chances of ischemic stroke statins like atorvastatin must be to control the levels of low density lipoproteins.

Keywords


stroke, low density lipoproteins, intracerebral hemorrhage

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References


Doria, Joseph W., and Peter B. Forgacs. "Incidence, implications, and management of seizures following ischemic and hemorrhagic stroke." Current neurology and neuroscience reports 19, no. 7 (2019): 37.

Assy, Mohamed H., Mohamed Awd, Arafa M. Elshabrawy, and Mahmoud Gharieb. "Effect of Ramadan fasting on incidence of cerebrovascular stroke in Egyptian patients with Type 2 Diabetes Mellitus." Diabetes research and clinical practice 151 (2019): 299-304.

Luby, Marie, Amie W. Hsia, Zurab Nadareishvili, Kaylie Cullison, Noorie Pednekar, Malik Muhammad Adil, and Lawrence L. Latour. "Frequency of Blood-Brain Barrier Disruption Post-Endovascular Therapy and Multiple Thrombectomy Passes in Acute Ischemic Stroke Patients." Stroke 50, no. 8 (2019): 2241-2244.

Cortés-Vicente, Elena, Daniel Guisado-Alonso, Raquel Delgado-Mederos, Pol Camps-Renom, Luis Prats-Sánchez, Alejandro Martínez-Domeño, and Joan Martí-Fàbregas. "Frequency, risk factors and prognosis of dehydration in acute stroke." Frontiers in neurology 10 (2019): 305.

Huang, Wen-Yi, Jeffrey L. Saver, Yi-Ling Wu, Chun-Jen Lin, Meng Lee, and Bruce Ovbiagele. "Frequency of intracranial hemorrhage with low-dose aspirin in individuals without symptomatic cardiovascular disease: A systematic review and Meta-analysis." Jama Neurology 76, no. 8 (2019): 906-914.

Shah, Ali, Samurna Sabir, Moiz Artani, Osama Salam, Shehroz Khan, and Amber Rizwan. "Significance of hyponatremia as an independent factor in predicting short-term mortality in patients with hemorrhagic stroke." Cureus 11, no. 4 (2019).

Sahto, Abdul Aziz, and Amir Shahzad. "ISCHEMIC AND HEMORRHAGIC STROKE." The Professional Medical Journal 26, no. 02 (2019): 253-259.

Badve, Monica S., Zien Zhou, Diederik van de Beek, Craig S. Anderson, and Maree L. Hackett. "Frequency of post-stroke pneumonia: Systematic review and meta-analysis of observational studies." International Journal of Stroke 14, no. 2 (2019): 125-136.

Olesen, Kevin Kris Warnakula, Kamilla Steensig, Morten Madsen, Troels Thim, Lisette Okkels Jensen, Bent Raungaard, John Eikelboom, Steen Dalby Kristensen, Hans Erik Bøtker, and Michael Maeng. "Comparison of frequency of ischemic stroke in patients with versus without coronary heart disease and without atrial fibrillation." The American journal of cardiology 123, no. 1 (2019): 153-158.

Hudson, Joseph S., Timothy K. Chung, Benjamin S. Prout, Yasunori Nagahama, Madhavan L. Raghavan, and David M. Hasan. "Iron nanoparticle contrast enhanced microwave imaging for emergent stroke: A pilot study." Journal of Clinical Neuroscience 59 (2019): 284-290.

Malik, Moeen Akhtar, Akmal Hussain, Junaid Mustafa, Noreen Nasim, and Sohaib Asghar. "Frequency of Dyslipidemia in Hemorrhagic Stroke." Annals of Punjab Medical College 13, no. 3 (2019): 229-231.

Sugiyama, Mizuho, Yuji Ueno, Hikaru Kamo, Yoko Edahiro, Nobukazu Miyamoto, Kazuo Yamashiro, Ryota Tanaka, Yasushi Shimo, Norio Komatsu, and Nobutaka Hattori. "Specific mechanisms of subarachnoid hemorrhage accompanied by ischemic stroke in essential thrombocythemia: two case reports and a literature review." Journal of neurology 266, no. 8 (2019): 1869-1878.

Zhou, Jie, Meng-Meng Ma, Jing-Huan Fang, Lei Zhao, Mu-Ke Zhou, Jian Guo, and Li He. "Differences in brain-derived neurotrophic factor gene polymorphisms between acute ischemic stroke patients and healthy controls in the Han population of southwest China." Neural regeneration research 14, no. 8 (2019): 1404.

Chiu, Tina HT, Huai-Ren Chang, Ling-Yi Wang, Chia-Chen Chang, Ming-Nan Lin, and Chin-Lon Lin. "Vegetarian diet and incidence of total, ischemic, and hemorrhagic stroke in 2 cohorts in Taiwan." Neurology 94, no. 11 (2020): e1112-e1121.

Thakkar, Samarthkumar, Chintan Rupareliya, and Rajkumar Doshi. "Incidence and impact of ischemic and hemorrhagic stroke after left ventricular assist device implantation: A nationwide study." Indian Heart Journal (2019).


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