Endoscopic and Demographic features in H.Pylori positive Patients
Objective: The main aim of this study was to analyze the endoscopic and demographic features in H.Pylori patients.
Place and Duration of study: This study was carried out in a duration of 10 months from February 2019 to November 2019 in medical department of Mayo hospital Lahore.
Study type: It is a cross sectional type of study.
Sampling technique: Non probability sampling technique.
Material and Methods: A total of 100 patients were selected for this study. Both males and females were selected randomly. Patients with past history of aRa-H pylori treatment were excluded from this study. Past history of NSAID use over last three months was asked from the patients. Patients with positive history of NSAID or aspirin use over for 3 days during this period were taken as NSAID users. While performing endoscopy, eight samples were collected from all these patients using proper protocols. Serum samples were taken carefully and sent to a reliable laboratory for detection of H.Pylori IgG antibodies using ELISA. Histology and culture sensitivity, rapid urease test, demographic data, past history of NSAID use, serum anti H.Pylori IgG antibodies and number size and location of ulcers. All the data was collected and analyzed using SPSS version 20.
Results: A total of 100 patients were selected for this study and their data was carefully collected and analyzed. Among these 100 patients, H.Pylori was found in 67 patients and NSAID use was seen in 33 patients. Clinical, demographic and endoscopic data of patients with duodenal ulcers was collected. Positive smoking history was seen in around 22% of the patients who were using NSAIDS and were positive for H.Pylori and this is significantly higher than patients of H.Pylori alone. No significant difference in GI bleeding was seen among two groups.Conclusion: It can be concluded that frequency of gastric ulcers is mu h higher than duodenal ulcers. Older people are more prone to develop gastric ulcers following H.Pylori infection or NSAIDs use while among young people non-NSAID non-H.Pylori ulcers were more common.
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